
Why Testosterone Replacement Therapy Can Paradoxically Increase Estrogen
Testosterone replacement therapy can paradoxically surge estrogen levels. Learn how aromatase activity, adiposity, and zinc status govern androgen balance.
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Testosterone replacement therapy can paradoxically surge estrogen levels. Learn how aromatase activity, adiposity, and zinc status govern androgen balance.

Central to immunity, healing and hormone synthesis — and in direct competition with copper for absorption, which is why sustained high doses create a new deficiency.