
Upstream Causes of Constipation: Beyond Fiber to Gastric, Bile, and Autonomic Function
Chronic constipation is rarely just a fiber deficit; it reflects breakdowns in stomach acid, bile flow, pancreatic enzymes, or autonomic nervous system signaling.
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Chronic constipation is rarely just a fiber deficit; it reflects breakdowns in stomach acid, bile flow, pancreatic enzymes, or autonomic nervous system signaling.

Eating in a sympathetic stress response impairs digestive acid, enzyme secretion, and gut motility, altering postprandial metabolic signaling.

Sustained economic and political uncertainty activates the neuroendocrine stress response, promoting elevated cortisol, systemic inflammation, and cellular insulin resistance.