Tag

brain-health

3articles

September 8, 20264 min

Creatine Dosing for Brain Bioenergetics: Why Five Grams May Fall Short for Cognitive Stress

Standard five-gram daily creatine doses saturate muscle tissue but leave little for the brain; higher intakes are required to support cerebral energy metabolism during cognitive strain and sleep loss.

atp bioenergetics

August 8, 20264 min

Polyunsaturated Fatty Acids and Amyloid Markers in Mild Cognitive Impairment

Pooled clinical data shows polyunsaturated fatty acids alter amyloid-beta clearance and cognitive scores in mild cognitive impairment, though trial quality significantly impacts effect size.

amyloid beta brain-health

August 3, 20264 min

High-Dose DHA Enters Cerebrospinal Fluid but Fails to Prevent Cognitive Decline

High-dose DHA elevates cerebrospinal fluid fatty acid levels, but two years of supplementation fails to alter brain volume or cognitive trajectory in older adults.

apoe4 brain-health