Tag

ceramides

2articles

September 23, 20265 min

Lipotoxicity, Ceramides, and the Real Mechanism Behind Cellular Insulin Resistance

Cellular insulin resistance is driven by toxic lipid intermediates like ceramides and chronic hyperinsulinemia rather than passive energy overload.

ceramides hyperinsulinemia

August 22, 20265 min

Saturated Fat and Insulin Resistance: Cell Models vs. Human Physiology

Cell models show saturated fat impairing insulin signaling, but physiological gut digestion and liver lipogenesis reveal a very different story in humans.

ceramides de novo lipogenesis