How Gut Permeability Drives Hepatic Inflammation and Fatty Liver Disease
Increased gut permeability allows bacterial endotoxins into the portal vein, driving chronic hepatic inflammation and metabolic fat storage in the liver.
endotoxemia
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Increased gut permeability allows bacterial endotoxins into the portal vein, driving chronic hepatic inflammation and metabolic fat storage in the liver.
Lipopolysaccharides leaking from the gut trigger systemic inflammation, but LDL particles actively bind and excrete these bacterial toxins through the liver.